St. Louis Comedy Shows May 2027
Stand-up comedy, touring comedians, and live comedy shows in St. Louis and nearby areas.
- Updated: November 13, 2026
St. Louis comedy shows in May 2027 include stand-up comedians, improv performances, podcast tours, and live comedy events. Comedy performances take place across clubs, theaters, arenas, and entertainment venues throughout the city during the month.
- 8 Upcoming Shows
- Next Show Starts In:
- Matt Mathews
- May 14 · 7:00 PM · St. Louis, MO
- View Tickets
Comedy Shows By Dates
Upcoming Comedy Shows in May
Browse comedy shows by date and venue in St. Louis during May 2027.- May 14, 2027, 7:00 PM Fri — COMEDY, High Demand: Matt Mathews at Stifel Theatre • 3100 seats,
1400 Market Street, St. Louis, MO 63103, US. From $62, Avg. price ~ $347, Tickets Available: 269. Select Seats - May 14, 2027, 10:15 PM Fri — COMEDY: Matt Mathews at Stifel Theatre • 3100 seats, 1400 Market Street, St. Louis, MO 63103, US. From $62, Avg. price ~ $163, Tickets Available: 456. Select Seats
- May 20, 2027, 7:30 PM Thu — COMEDY, Best Value: Joe Fenti at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $48, Avg. price ~ $133, Tickets Available: 118. Select Seats
- May 27, 2027, 7:30 PM Thu — COMEDY: Usama Siddiquee at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $56, Avg. price ~ $130, Tickets Available: 40. Select Seats
- May 28, 2027, 7:00 PM Fri — COMEDY: Usama Siddiquee at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $56, Avg. price ~ $94, Tickets Available: 36. Select Seats
- May 28, 2027, 9:15 PM Fri — COMEDY: Usama Siddiquee at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $56, Avg. price ~ $130, Tickets Available: 40. Select Seats
- May 29, 2027, 7:00 PM Sat — COMEDY, Weekend Event: Usama Siddiquee at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $56, Avg. price ~ $94, Tickets Available: 36. Select Seats
- May 29, 2027, 9:30 PM Sat — COMEDY, Weekend Event: Usama Siddiquee at Helium Comedy Club - St. Louis, 1151 St Louis Galleria Street, St. Louis, MO 63117, US. From $56, Avg. price ~ $130, Tickets Available: 40. Select Seats
All Comedy Shows in May
Comedy Clubs & Venues
Comedy Shows FAQ
What comedy shows are happening in St. Louis during May 2027?
Comedy schedules may include stand-up comedians, touring comedy acts, improv performances, podcast tours, and live comedy specials across St. Louis and nearby areas.
Are comedy schedules updated regularly?
Yeah. New comedy performances and additional dates are added often as venues announce updated schedules and special events throughout May.
What types of comedy performances are included?
You’ll commonly find stand-up comedy, improv shows, podcast recordings, sketch comedy, and performances by touring comedians.
Where are comedy shows usually performed in St. Louis?
Comedy events are often hosted at comedy clubs, theatres, casinos, bars, resorts, and entertainment venues throughout St. Louis.
Do comedy shows happen during the week?
Absolutely. Many comedy venues host performances throughout the week, while weekends are usually the busiest nights for live comedy.
Do major comedians tour through St. Louis?
Yes. National touring comedians and comedy acts regularly perform in St. Louis during May 2027.